GRUB is a relatively new boot loader, for x86. Depending on how GRUB is installed, it may understand the file system, or simply remember where the boot files are stored. It understands the file system if it's using "Stage1.5". If it's not using Stage1.5, or the partition number changes, then you need to reinstall Stage2 (please see the GRUB documentation). Otherwise, you don't need to do anything.
GRUB automatically detects if LBA is available, and will use it if it is available (equivalent to LILO's "lba32" option).
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